Kagan, Soai Win 2026 Nobel Chemistry Prize for Solving Century-Old Molecular Mystery

French and Japanese scientists honoured for discoveries that explain how one form of ‘mirror-image’ molecule can dominate in nature.

October 7, 2026 at 7:40 PM
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STOCKHOLM, Sweden: French scientist Henri B. Kagan and Japanese chemist Kenso Soai have won the 2026 Nobel Prize in Chemistry for discovering non-linear effects and autocatalysis in asymmetric organic synthesis, helping solve a century-old mystery about how molecules acquire a single “handedness”.

The Royal Swedish Academy of Sciences announced the award on Wednesday, praising the scientists for research that has transformed understanding of chirality, a property in which molecules exist in two forms that are mirror images of each other.

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A century-old chemical mystery

The Nobel Committee said Kagan and Soai had provided an important solution to the long-standing question of how homochirality can emerge spontaneously — why living systems tend to use only one of two possible mirror-image forms of certain molecules.

“Henri Kagan and Kenso Soai have provided a solution to a chemical mystery that is over a century old: how homochirality can emerge spontaneously,” Heiner Linke, chair of the Nobel Committee for Chemistry, said.

“The chemical reactions they have developed are spectacular.”

Kagan is affiliated with Université Paris-Sud in Orsay, France, while Soai is associated with the Tokyo University of Science. Soai is 95 years old.

Research with major pharmaceutical implications

Their work has significant implications for chemistry and pharmaceutical research because mirror-image versions of the same molecule can behave very differently in the human body. The ability to control which molecular form is produced is therefore important in developing medicines and other biologically active compounds.

Kagan’s research in the 1980s showed how a small imbalance between mirror-image molecules could be amplified during chemical reactions. Soai later demonstrated how a molecule could act as a catalyst to produce more molecules with the same molecular “handedness”, leading to what became known as the Soai reaction.

The laureates will share the Nobel prize award of 12 million Swedish kronor, equivalent to about $1.2 million, along with the Nobel medal and diploma.

Other 2026 Nobel winners

The Chemistry announcement followed the 2026 Nobel Prize in Physiology or Medicine, awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel, and the 2026 Nobel Prize in Physics, awarded to Francis Halzen.

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The remaining 2026 prizes, Literature, Peace and the Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel, were scheduled for announcement later in the week.

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